Dedicated to Scientific Excellence, Innovation, and the Pursuit of Knowledge for a Better World

07:00 PM - 09:00 PM
Opening Dinner
Location: Hanul lui Manuc

A warm welcome for our international guests, hosted within the picturesque and traditional Romanian atmosphere of Bucharest's historic Manuc's Inn.

08:30 AM - 09:15 AM
Opening and Registration
Location: Conference Room - Research Platform in Systems Biology and Ecology

Welcome Addresses:
Prof. Liliana Burlibasa (Dean, Faculty of Biology, University Bucharest, Romania)
Prof. Dr. Derek J. Hausenloy (National Heart Center, Singapore)
Prof. Dr. Klaus T. Preissner (Justus-Liebig-University, Giessen, Germany)
Prof. Dr. Elisa A. Liehn (National Heart Center, Singapore)

09:15 AM - 10:45 AM
Session 1: Heart Protection - Regeneration
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: Carl Wilhelm Vogel (Hawaii, USA) & Elisa Liehn (Singapore)

1.1 Derek J. Hausenloy (Singapore)
Discovering novel treatment targets for heart failure using patient stem cells

1.2 Klaus T. Preissner (Giessen, Germany)
The extracellular RNA/RNase1 interplay in cardiovascular protection

1.3 Peter Ferdinandy (Budapest, Hungary)
Development of miRNA therapeutics for cardioprotection. A progress report

1.4 Sven Reischauer (Giessen, Germany)
Fibrosis limits tissue regeneration or vice versa? Insights from the cardiac stroma during heart regeneration in zebrafish

10:45 AM - 11:15 AM
Coffee Break and Poster viewing and moderation session (I)
Location: Lobby - Conference Room - Research Platform in Systems Biology and Ecology

Our distinguished guests will be available for engaging and meaningful discussions, so please do not hesitate to approach them and take the opportunity to network.

A review committee will carefully evaluate our students' research projects and provide constructive feedback and recommendations. We encourage you to enjoy this valuable experience.

11:15 AM - 12:45 PM
Session 2: Cardiovascular Disease
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: Hector A. Cabrera-Fuentes (Mexico) & Zsuzsanna Helyes (Pécs, Hungary)

2.1 William A. Boisvert (Hawaii, USA)
Endothelial lipid metabolism in atherosclerosis

2.2 Alexandrina Burlacu (Bucharest, Romania)
From cancer to heart fibrosis- Glioma-Pathogenesis Related Protein 1 highlights a subset of myofibroblasts responsive to mesenchymal stem cell therapy after myocardial infarction

2.3 Elisabeth Deindl (Munich, Germany)
Gamma-delta T-cells in arteriogenesis

2.4 Rainer Schulz (Giessen, Germany)
Cardiac side effects of RNA-based vaccines

12:45 PM - 02:00 PM
Lunch Break and Poster viewing and moderation session (II)
Location: Lobby - Conference Room - Research Platform in Systems Biology and Ecology

Our distinguished guests will be available for engaging and meaningful discussions, so please do not hesitate to approach them and take the opportunity to network.

A review committee will carefully evaluate our students' research projects and provide constructive feedback and recommendations. We encourage you to enjoy this valuable experience.

02:00 PM - 03:30 PM
Session 3: Mechanisms of Cardiovascular Disease I
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: William A. Boisvert (Hawaii, USA) & Coert Zuurbier (Amsterdam, Netherlands)

3.1 Elisa Liehn (Singapore)
The Phosphatidylserine role in cardioprotection

3.2 Manvendra Singh (Singapore)
Hippo Signaling mediators Yap/Taz in pulmonary inflammation and fibrosis

3.3 Belman Turan (Ankara, Turkey)
An important off-target action of a dual GLP-1/GIP reeptor agonist on elderly heart function

3.4 Hector Cabreras-Fuentes (Mexico)
Extracellular RNA as a therapeutic target during cardiac reperfusion

03:15 PM - 03:45 PM
Coffee Break
Location: Lobby - Conference Room - Research Platform in Systems Biology and Ecology

Our distinguished guests will be available for engaging and meaningful discussions, so please do not hesitate to approach them and take the opportunity to network.

03:45 PM - 05:15 PM
Session 4: Mechanisms of Cardiovascular Disease II
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: Klaus T. Preissner (Giessen, Germany) & Manvendra Singh (Singapore)

4.1 Ece Yurtseven (Istanbul, Turkey)
PCSK9 in atherosclerosis

4.2 Zsuzsanna Helyes (Pécs, Hungary)
Sub-antimicrobial dose doxycycline inhibits chronic smoke-induced cardiopulmonary comorbidities in a mouse model: role of matrix metalloproteinases?

4.3 Jiong-Wei Wang (Singapore)
Targeted modulation of ceramide synthesis in cardiovascular disease

4.4 Ioana Streata (Craiova, Romania)
From research to diagnostic to in cardiogenetics : single center experience

07:00 PM - 09:00 PM
Networking Event
Location: Carul cu Bere

Our guests will experience a vibrant and enjoyable Social Evening celebrating Romanian culture at "Carul cu Bere", Bucharest.

09:00 AM - 10:30 AM
Session 5: Cardiovascular – Organ Interplay
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: Peter Ferdinandy (Budapest, Hungary) & Shiang Y. Lim (Melbourne, Australia)

5.1 Bucur Octavian (Bucharest, Romania)
Genomics Research and Development Institute: strategic research and translational impact

5.2 Paul Yen (Singapore)
Hepatokines in Metabolic Dysfunction-associated Steatohepatits (MASH) and their roles in HFpEF (heart failure with preserved ejection fraction)

5.3 Saime Batirel (Istanbul, Turkey)
Exploring the gut–heart axis: Linking incretins and lipid metabolism to coronary artery disease severity

5.4 Roshni R. Singaraja (Singapore)
Semaphorin in the vascular wall

10:30 AM - 10:45 AM
Coffee Break
Location: Lobby - Conference Room - Research Platform in Systems Biology and Ecology

Our distinguished guests will be available for engaging and meaningful discussions, so please do not hesitate to approach them and take the opportunity to network.

10:45 AM - 12:00 PM
Session 6: Young Investigators` Presentations
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chairs: Hector A. Cabrera-Fuentes (Mexico), Klaus T. Preissner (Giessen, Germany)

The top five abstracts have been selected for an exclusive presentation in the prestigious Young Investigators Session!

1. Roberta Moisă

Human brain endothelial cells exhibit elevated radiosensitivity compared to murine model under X-Ray exposure
Moisa R, Pătrașcu S, Radu M, Radu BM
Department of Life and Environmental Physics, ‘Horia Hulubei’ National Institute for Physics and Nuclear Engineering, Măgurele, Romania; Department of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania; Department of Radioisotopes and Radiation Metrology, ‘Horia Hulubei’ National Institute for Physics and Nuclear Engineering, Măgurele, Romania

2. Cătălina Marinescu-Colan

From cancer to infarcted hearts: GLIPR1 as a detrimental regulator in activated cells
Marinescu-Colan CI, Nastase-Rusu EG, Neculachi CA, Preda MB, Burlacu A
Department of Stem Cell Biology, Institute of Cellular Biology and Pathology “Nicolae Simionescu”, Bucharest, Romania:

3. Andreea Trifan

From Bone to Beyond: Exploring CaP-Hydrogel Scaffolds and 3D Bioprinting for Regenerative Medicine
Trifan A
3D Printing Laboratory, Center of Innovation and e-Health, „Carol Davila” University of Medicine and Pharmacy of Bucharest, Romania; Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica of Bucharest, Romania

4. Victor Gabriel Ungureanu

Three-Dimensional Reconstruction of Pulmonary Microvasculature in Group I Pulmonary Arterial Hypertension
Victor Gabriel Ungureanu, Elisa Liehn, Miron Alexandru Bogdan, Octavian Bucur
Genomics Research and Development Institute, Bucharest, Romania; Elias University Emergency Hospital, Bucharest, Romania; National Heart Center Singapore; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Marius Nasta Institute of Pneumology, Bucharest, Romania; Viron Molecular Medicine Institute, Boston, USA

5. Elisa Octavia Velicu

Lipid Defense: The Power of Phosphatidylserine Against Atherosclerosis Through LDL Interaction
Velicu EO, Pistritu D, Ringaraja R, Mayan DC, Liehn EA
University of Medicine and Pharmacy Carol Davila Bucharest, Romania, National University of Singapore, National Heart Center Singapore

12:00 PM - 01:00 PM
Lunch Break
Location: Lobby - Conference Room - Research Platform in Systems Biology and Ecology

Our distinguished guests will be available for engaging and meaningful discussions, so please do not hesitate to approach them and take the opportunity to network.

01:00 PM - 02:30 PM
Visite to the Parliament Palace for International Guests
Location: Parliament Palace

Our international guests will enjoy a distinguished and memorable experience through a guided tour of the Parliament Palace.

02:30 PM - 04:00 PM
Session 7: Technologies & Theranostics
Location: Conference Room - Research Platform in Systems Biology and Ecology

Chair: Derek J. Hausenloy (Singapore) & Ece Yurtseven (Istanbul, Turkey)

7.1 Alexandru Scafa (Bucharest, Romania)
The role of coronary collaterals in preserving myocardial viability in patients with coronary syndromes

7.2 Coert Zuurbier (Amsterdam, Netherlands)
Developing multi-target reperfusion therapy in rat cardiac I/R model with clinical relevant anesthesia

7.3 Shiang Y. Lim (Melbourne, Australia)
Sustained secretome therapy via device-encapsulated stem cells for long-term cardioprotection

7.4 Bogdan Amuzescu (Bucharest, Romania)
In vitro and in silico cardiac safety drug testing: advancing the CiPA paradigm

04:00 PM - 05:00 PM
Session 8: Poster Awards and Concluding remarks
Location: Auditorium Faculty of Biology

Our distinguished guests will recognise outstanding students by presenting awards to promote their professional development.

Three Best Poster Awards will be conferred, and one Young Investigator Award.

Announcement: 10th Meeting “New Frontiers in Cardiovascular Research” in Lima/Peru.

Concluding remarks
Derek J. Hausenloy (Singapore)
Klaus T. Preissner (Germany)
Hector Cabrera-Fuentes (Mexico)
Elisa Liehn (Singapore)
Beatrice M. Radu (Bucharest)

We hope that the connections made here will inspire future innovations and continued cooperation.

07:30 PM - 10:00 PM
Romanian Private Celebration
Location: Privat address

We're excited to create an unforgettable experience exclusively for our international guests, featuring lively Romanian music, energetic dancing, delicious Romanian food, and rich cultural traditions. It's a special celebration to remember!

08:00 AM - 08:00 PM
Networking and Social Event - Meet Romania
Location: Bucharest - Sinaia - Bran - Brasov

Our international guests will have the opportunity to immerse themselves in the richness and warmth of Romanian culture through an unforgettable journey to significant heritage sites, including Bran, Sinaia, and Brașov.